Platelet-Rich Plasma or PRP is an "autologous blood therapy" that uses a patient's own blood components to stimulate a healing response in damaged tissues.
In response to an injury or tissue damage, your body naturally recruits platelets and white blood cells from the blood to initiate a healing response. Under normal conditions, platelets store numerous growth factors which are released in response to signals from the injured tissue. Modern technology allows us to concentrate platelets from your blood, and induce this growth factor release as the solution is injected into injured tissue, simulating this same healing response in a more powerful form.
Platelet injection therapy has changed the way orthopedic specialists treat sports injury patients. The use of minimally invasive protocols that involve ultrasonically guided platelet rich plasma (PRP) injections has provided the first regenerative treatment for damaged muscle, tendon, ligament and soft–tissue injuries. When PRP is injected into the damaged area it stimulates the tendon, ligament or muscle with a high concentration of growth factors that triggers the healing cascade. As a result new tissue begins to develop. As this tissue matures it begins to shrink causing the tightening and strengthening of the tendons, ligaments and muscle of the damaged area.
To prepare PRP, a small amount of blood is taken from the patient. The blood is then placed in a centrifuge. The centrifuge spins and through a multi-functional process separates the plasma from the blood producing the PRP. Once the platelets are concentrated, the preparation is then injected into the injured body part, frequently under ultrasound guidance.
Depending on the severity and duration of your injury, one to three PRP injections are suggested. Following the initial treatment with PRP, a follow up visit occurs two to threee weeks later. At this visit an evaluation of your response to the initial therapy is performed and a decision is made regarding the need for additional PRP treatments. Frequently, chronic injuries require more than one injection. In both acute and chronic injuries, injections may be combined with an exercise or physical therapy program to enhance the success of the treatment.
Research and clinical data show that PRP injections are extremely safe, with minimal risk for any adverse reaction or complication. Because PRP is produced from your own blood, there is no concern for rejection or disease transmission. There is a small risk of infection from any injection into the body, but this is rare. Of note, recent research suggests that PRP may have an anti-bacterial property which protects against possible infection.
Recent studies suggest that PRP is bactericidal to Staphylococcus and Pseudomonas: "Platelet rich plasma appears to be effective in preventing growth of Pseudomonas and Staphylococcus Aureus. Bactericidal effects are also noted."